Frequently Asked Questions


What can we learn from how the previous successful GWAS projects did?

We are looking to learn all the (good) lessons that previous projects can teach us. One good example that we are aware of is the UK GLAD study, which has used predominantly online recruitment. One year in, 79,000 people had registered online, 47,400 had given consent and 20,000 people had returned saliva samples to become study participants.

The GLAD study is recruiting from the 1 in 3 people aged 16+ who have ever had anxiety or depression (18 million), while we have the much more challenging task of recruiting from the approximately 1 in 250 people who have ME/CFS. Even so, the GLAD study’s recruitment is at least a proof of concept, and also gives examples of ways of engagement that will be useful to us in our study, though the disease focus of the research is very different.

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The largest ever DNA study of ME/CFS

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