Join the world’s largest genetic ME/CFS study

We aim to find genetic causes of why people become ill with myalgic encephalomyelitis (ME) / Chronic Fatigue Syndrome (CFS) with our groundbreaking research. Join us from your home.

We have secured funding for a very large study to analyse DNA from the saliva of people with ME/CFS to see whether the disease is partly genetic and, if so, help pinpoint what causes it. The study should help us understand the disease and ultimately find treatments.

The big 20k people

We need 20,000 participants – and people to help us find them. The study involves filling in a questionnaire and providing a saliva sample - both from home.

The study is now even bigger. We’re expanding the study to include up to 5,000 people who develop ME/CFS after a Covid-19 infection.

A female scientist in a laboratory

The largest ever DNA study of ME/CFS

DNA molecule formed by chains of people

The research

The study is being led by Professor Chris Ponting of the Medical Research Council Human Genetics Unit at the University of Edinburgh.

People with myalgic encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) are at the heart of the study, with a patient and a carer as co-investigators alongside the scientists and a steering group of people with the illness, carers and charities.

The research is funded by the Medical Research Council and the National Institute for Health Research. To find out more, read our latest updates, FAQs and explanation of the science.

Register your interest

You must be 16 or over to take part. If you're in the UK, you'll be first to know when recruitment opens. If you're outside the UK, we'll let you know if there's a chance to take part in future.

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A partnership between

Action for ME logo
Forward ME Logo
UKRI MRC Human Genetics Unit logo
National Institute for health research