ME/CFS is a complex condition, so from the beginning of DecodeME, we didn’t expect to find just one gene responsible. Like other conditions such as Parkinson’s or diabetes, ME/CFS is influenced by small differences in several genes rather than in one gene only. In DecodeME, we looked at over 8 million points across the genome and found 8 regions, where people with ME/CFS were more likely to have certain genetic differences. These regions give us important clues about the biological processes that may be involved in the illness.
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